🏆 International Grants:
- Principal Investigator of Project : Mapping the inflammation and epigenetic landscape of gestational Diabetes mellitus in Indian mothers and their babies
🏆 Research In Progress:
1.To study the ultra and molecular changes in bone of T2DM and propose preventive and treatment strategy to overcome fragility fracture based on assessment of bone quality and quantity, mechanical properties, remodeling indices as well as genomic data in T2DM.
2. Evaluation of polycomb repressive complex 2 PRC2 target genes as potential epigenetic regulators of sporadic primary hyperparathyroidism
3. Development of Nano-enabled Teriparatide-Loaded Pharmaceutical Product for Osteoporosis: An approach to reduce the dosefrequency with better patient compliance therapeutic efficacy.
4. A life style intervention program for the prevention of type-2 diabetes mellitus among South Asian women with gestational mellitus.
5. Penetrance of susceptibility and protective genes in familiar clustering of Type 1 diabetes and it’s co-association with celiac disease.
6. Framework for Developing Training Model to Strengthen Diabetic Retinopathy Screening and Research in North India.
Extramural Projects:
1. Principal Investigator of ICMR Project : To identify COVID-19 perturbed genes and immune-repertoire networks in diabetes and obesity-associated severe infections
2. Principal Investigator of DHR Project : To study the ultra and molecular changes in bone of T2DM and propose preventive and treatment strategy to overcome fragility fracture based on assessment of bone quality and quantity, mechanical properties, remodeling indices as well as genomic data in T2DM. (File number : GIA/2019/000111/PRCGIA)
3. Principal Investigator of ICMR Project : Evaluation of polycomb repressive complex 2 PRC 2 target genes as potential epigenetic regulators of sporadic primary hyperparathyroidism.
4. Principal Investigator of ICMR Task force Project Penetrance of susceptibility and protective genes in familiar clustering of Type 1 diabetes and it’s coassociation with celiac disease. (From July 2019- July 2021)
5. Principal Investigator of ICMR Project : Development of Nano-enabled Teriparatide-Loaded Pharmaceutical Product for Osteoporosis: An approach to reduce the dose frequency with better patient compliance therapeutic efficacy Project ID 2018-1097.
6. Principal Co-Investigator of SPARC Project : Framework for Developing Training Model to Strengthen Diabetic Retinopathy Screening and Research in North India. Project ID :1155.
7. Principal Investigator of DST-SERB Project : Identification of Potential Epigenetic Biomarkers for Detection and Diagnosis of Primary Hyperparathyroidism (File number: EMR/2016/005956)
8. Principal Investigator of ICMR Project: : A life style intervention program for the prevention of type-2 diabetes mellitus among South Asian women with gestational mellitus (ICMR/2016/)
9. Principal Investigator of ICMR Project : VDR and Calcium Sensing Receptor (CaSR) in patients with Primary Hyperparathyroidism (PHPT) and its correlation with clinical outcome.
10. Co-Principal Investigator of ICMR Project : Registry of People with Diabetes in India with Young Age at Onset.
11. Principal Investigator of ICMR Project : Identification of differentially expressed proteins in parathyroid tumors and their clinical correlation with the disease.
12. Principal Investigator of UT-Department of Science & Technology : To Study the Prevalence of Osteoporosis in Diabetes Mellitus in Area Of UT Chandigarh.
13. Principal Investigator of RSSDI : To Study the prevalence Of Osteoporosis In Diabetes Mellitus In Area Of UT Chandigarh.
14. Principal Investigator of ESI : Expression profiling of mitogen activated protein kinase (MAPK) pathway signalling molecules in patients with sporadic primary Hyperparathyroidism.
🏆 Departmental / P.G.I Projects
1. Principal Investigator of PGIMER Project : To study the role of Androgens in pathogenesis and molecular mechanism of osteoporosis in obese men (No.71/2-Edu-16).
2. Principal Investigator of PGIMER Project : To study the methylation status of CDKN2A, CDKN2B and RASSFIK in patients with Primary Hyperparathyroidism (PHPT).
3. Principal Investigator of PGIMER Project: Efficacy and safety of the umbilical cord blood derived mesenchymal stem cells in Type 1 diabetes.
4. Principal Investigator of PGIMER Project : Functional and genetic characterization of microRNAs involved in sporadic parathyroids tumours (No. 71/8-Edu-15/1637).
5. Principal Investigator of Indian PHPT Registry (www.indianphptregistry.com) : it is online self sustained multicentric registry for primary hyperparathyroid patients to understand natural history and pathogenesis of primary hyperparathyroidism in India.
6. Principal Investigator of rare metabolic bone disease registry (www.rarembdregistry.org) : an online self sustained registry for patients with rare metabolic bone disorders to understand natural history and molecular genetics of rare metabolic bone disease patients.